How does Tramadol work? Tramadol Dosage and Side effects


Tramadol has a nature to relieve Pain. It Functions by increasing the levels of two natural chemicals, namely, serotonin and neurotransmitters norepinephrine. And Thus this changes the way your brain reacts and responds to the pain signals transmitted by your central nervous system (CNS). Making You Feel relaxed and reduces pain to make you feel better overall.

It comes in tablets, capsules and injectable forms. The most preferred way to administer Tramadol is by mouth (Orally) with or without food by swallowing.

Administer it strictly as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing or chewing as it may cause an overdose by metabolized faster and reached your bloodstream concentration quicker than expected. It may cause life-threatening side effects.

Do not take more doses than prescribed. Do not stop administering the drug abruptly except on the advice of your doctor. This may cause severe Tramadol withdrawal symptoms.

It may need more time for the medication to help you. Do not stop the doses suddenly before speaking to your doctor.

It is available in immediate-relief and extended-relief form.

Precautions Before Tramadol Administration.

Before taking this medication know about its dosage and side effects, do inform your doctor or chemist if you are allergic; or if you have other allergies. Your doctor should know if you have heart, liver, or kidney problems.

Do not mix alcohol, smoking, administering anti-anxiety drugs, anti-depressant or other substances while being treated with this medication.

Caution is recommended before administering by pregnant/nursing women or children. Tramadol for elderly may be more sensitive to the side effects of the medicine.

During pregnancy, this treatment should be used only when strongly recommended and no other pain killers are working to offer the desired results.

Pregnant or planning to get pregnant should not administer this medicine unless prescribed by a doctor.

Tramadol Side Effects

The most common side effects are dizziness, nausea, constipation, and headache.

Tramadol Side Effects

Serious Side Effects

  • Seizures
  • Trouble breathing
  • Symptoms of serotonin syndrome
  • agitation
  • fever
  • nausea
  • muscle stiffness
  • lack of coordination
  • loss of consciousness
  • Chest pain
  • Rapid heartbeat
  • Extreme drowsiness
  • Fainting
  • Swelling of the face, tongue, throat, or extremities
  • Hallucinations
  • Severe rash
  • Thoughts of suicide

Get in touch with your doctor immediately if you see the aforesaid side effects in you or in your family member administering this medication.

Other Side Effects Include:

  • Sleepiness
  • Vomiting
  • Itching
  • Sweating
  • Feeling agitated
  • Nervousness
  • High
  • Indigestion
  • Dry mouth
  • Diarrhea
  • Sleeplessness
  • Tremor
  • Loss of appetite

Missed a dose of Tramadol?

In case of missed tramadol doses, take it as soon as you discover it. If you see that it is the time for the next scheduled dose, then better you skip the missed dose and go as per your usual scheduled dose. Do not take your dose twice as it may cause Tramadol overdose.


If you think you have overdosed the medication, seek emergency medical attention immediately.

The Symptoms of Overdose Usually Include:

  • Chest pain
  • Nausea
  • Irregular heartbeat
  • Feeling light-headedness
  • Fainting


Tramadol, if not taken under administration by a doctor can lead to harmful effects on mental as well as physical well-being. The above mentioned side- effects differs from person to person and should seek immediate medical help if the condition worsens.


  • Ribeiro, C.; Santos, C.; Gonçalves, V.; Ramos, A.; Afonso, C.; Tiritan, M.E. Chiral Drug Analysis in Forensic Chemistry: An Overview. Molecules 2018, 23, 262.
  • Ribeiro C, Santos C, Gonçalves V, Ramos A, Afonso C, Tiritan ME. Chiral Drug Analysis in Forensic Chemistry: An Overview. Molecules. 2018; 23(2):262.
  • Ribeiro, Cláudia, Cristiana Santos, Valter Gonçalves, Ana Ramos, Carlos Afonso, and Maria E. Tiritan 2018. “Chiral Drug Analysis in Forensic Chemistry: An Overview” Molecules 23, no. 2: 262.